书目名称 | Directed Enzyme Evolution: Advances and Applications |
编辑 | Miguel Alcalde |
视频video | http://file.papertrans.cn/281/280661/280661.mp4 |
概述 | Offers a comprehensive view on directed evolution in the biotechnological ground.Presents a state of the art summary of the methodical advances in this thrilling research field.Highlights the most sig |
图书封面 |  |
描述 | .This book focuses on some of the most significant advances in enzyme engineering that have been achieved through directed evolution and hybrid approaches. On the 25th anniversary of the discovery of directed evolution, this volume is a tribute to the pioneers of this thrilling research field, and at the same time provides a comprehensive overview of current research and the state of the art..Directed molecular evolution has become the most reliable and robust method to tailor enzymes, metabolic pathways or even whole microorganisms with improved traits. By mirroring the Darwinian algorithm of natural selection on a laboratory scale, new biomolecules of invaluable biotechnological interest can now be engineered in a manner that surpasses the boundaries of nature..The volume is divided into two sections, the first of which provides an update on recent successful cases of enzyme ensembles from different areas of the biotechnological spectrum, including tryptophan synthases, unspecific peroxygenases, phytases, therapeutic enzymes, stereoselective enzymes and CO2-fixing enzymes. This section also provides information on the directed evolution of whole cells. The second section of the b |
出版日期 | Book 2017 |
关键词 | biocatalysis; biomolecular screening; industrial biotechnology; protein engineering; semi-rational appro |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-50413-1 |
isbn_softcover | 978-3-319-84395-7 |
isbn_ebook | 978-3-319-50413-1 |
copyright | Springer International Publishing AG 2017 |