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Titlebook: Direct Oral Anticoagulants; From Pharmacology to Riccardo Proietti,Ahmed AlTurki,T. Jared Bunch Book 2021 Springer Nature Switzerland AG 20

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The Community Street Soccer Programted patients who present with life-threatening bleeding or with indication for emergent surgery. We will also review the mechanism of action and data supporting the use of specific reversal agents, nonspecific pro-hemostatic therapies including prothrombin complex concentrate, and future research av
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William J. Moreau,Dustin Nabhanarin, showing a better safety profile. Patients with atrial fibrillation on dialysis have been traditionally treated with warfarin, but its effectiveness for stroke prevention in this population is questionable. Some retrospective studies showed promising results with apixaban, but years will be nee
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Katherine M. Edenfield,Jocelyn R. Gravleerapeutic range is associated with less dementia. This potentially reflects a reduction in the risk of micro thromboembolisms and microvascular bleeds, respectively. Direct oral anticoagulants (DOACs) have been shown to be superior or noninferior to warfarin in reducing the risk of thromboembolism an
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Andrew Pasternak,Brian J. Krabaking in all surgeries. Therefore, NOAC interruption involves timing the cessation and reinitiation of the drug based on the predicted clearance, which takes renal function into account. In patients with normal renal function undergoing a low bleeding risk procedure, the usual practice is to discontin
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Anna L. Waterbrook,Moira Davenport low overall risk who undergo ablation but the optimal anticoagulation strategy in patients post AF ablation has not been determined. An ongoing trial will evaluate whether cessation of DOAC is safe post ablation.
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Sportswomen’s Apparel Around the Worldntiplatelet therapy aiming to achieve the best balance between bleeding and ischemic risk. However, in the DOAC era, the optimal management of AF patients requiring PCI is still debated, and ongoing studies and meta-analysis will probably change the landscape in the near future. The aim of this chap
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