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Titlebook: Direct Oral Anticoagulants; From Pharmacology to Riccardo Proietti,Ahmed AlTurki,T. Jared Bunch Book 2021 Springer Nature Switzerland AG 20

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书目名称Direct Oral Anticoagulants
副标题From Pharmacology to
编辑Riccardo Proietti,Ahmed AlTurki,T. Jared Bunch
视频video
概述Assesses important drug-drug interactions in patients with chronic kidney disease and cancer.Provides concise easy to digest information on the use of DOACs in perioperative management.Details the app
图书封面Titlebook: Direct Oral Anticoagulants; From Pharmacology to Riccardo Proietti,Ahmed AlTurki,T. Jared Bunch Book 2021 Springer Nature Switzerland AG 20
描述.This book concisely covers the latest developments in the application of direct oral anticoagulants (DOACs) within cardiovascular medicine. It details the pharmacodynamics and pharmacokinetic mechanisms of DOACs and their application in treating patients with conditions ranging from coronary heart disease through kidney disease and cancer, including their perioperative management. .Direct Oral Anticoagulants: From Pharmacology to Clinical Practice .systematically describes the underlying mechanisms associated with DOACs and their use to treat a range of conditions and is an indispensable resource for all trainee and practicing physicians in a range of disciplines seeking a concise up-to-date resource on the topic.  .
出版日期Book 2021
关键词Apixaban; Dabigatran; Edoxaban; Rivaroxaban; Atrial fibrillation; Stroke prevention; DOAC; Direct Oral Anti
版次1
doihttps://doi.org/10.1007/978-3-030-74462-5
isbn_softcover978-3-030-74464-9
isbn_ebook978-3-030-74462-5
copyrightSpringer Nature Switzerland AG 2021
The information of publication is updating

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Pharmacokinetics and Pharmacodynamics of DOAC, dabigatran (a reversible direct thrombin inhibitor) and the direct factor Xa inhibitors rivaroxaban, apixaban, and edoxaban offer fixed dosing, more predictable pharmacokinetics and fewer interactions with drugs and food than warfarin. Results from clinical trials demonstrated an improved benefit-r
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Risk Stratification For and Use of DOAC Therapies for Stroke Prevention in Patient with Atrial Fibrant agents play a key role in preventing this complication. Through years, several risk stratification algorithms have been investigated, while others are still object of debate. According to current guidelines, CHA2DS2VASc score and HAS-BLED score are the ones suggested for stroke and bleeding risk
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Use of DOAC in Patients with Kidney Disease,morrhagic events are increased in patients with kidney disease. Oral anticoagulation therapy, nowadays preferably with direct oral anticoagulants (DOACs), represents the cornerstone for ischemic stroke prevention in high-risk patients. However, all four available DOACs (dabigatran, apixaban, rivarox
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,The “Obesity Paradox” and the Use of NOAC,ovascular (CV) risk, more and more evidences suggest a favorable prognosis in obese subjects with cardiovascular disease (CVD), a phenomenon known as “obesity paradox.” Obesity paradox has been demonstrated in various CVD including atrial fibrillation (AF) and venous thromboembolism (VTE) for which
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