Titlebook: Diagnostic and Therapeutic Antibodies; Andrew J. T. George,Catherine E. Urch Book 2000 Humana Press 2000

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Antibodies for ImmunoassaysAn immunoassay is an analytical technique, quantitative or qualitative, that relies absolutely on the specificity and affinity of the interaction between epitope and paratope for generation of a detectable response. The actual detection of this binding interaction can be via one of literally hundred

想象

Intellectual Propertyexpression of ideas, and the inventors of such ideas (.). Intellectual property has many of the characteristics of real property (houses, buildings, and so forth); intellectual property can be bought, sold, assigned, and licensed. Additionally, the owner of IP can prevent “trespass” on his property

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From Laboratory to Clinic, passive antibody therapy was developed as an effective treatment for infectious diseases and for neutralization of toxins, and continues to be used to this day. Meanwhile, there have been continued efforts to use antibodies for cancer therapy, starting with the pioneering work of Hericourt and Ric

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Purification of Monoclonal Antibodies Using Protein A/Ghe fusion of B cells (secreting the relevant mAb) with a nonsecreting myeloma cell line (.). Since then mAbs have become a central tool for researchers, enabling them to investigate previously unknown molecules. More recently mAbs have also gained an important role in medicine, e.g., in helping to p

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Preparation of Monoclonal Antibodies Using Ion Exchange Chromatography reaction of immunoglobulins with immobilized ligands, as is the case of adsorption chromatography, which uses either protein A or G, but on the charge of the biomolecules. Some immunoglobulins bind only weakly or not at all to protein A or G, and for these molecules ion exchange is the method of ch

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Antibodies for Inflammatory Diseaseentification of potential target molecules and the immunotherapeutic mechanisms to be recruited by antibodies targeting these molecules. Regardless of the target antigen, antibodies may modify immune responses by:

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Diagnostic and Therapeutic Antibodies978-1-59259-076-6Series ISSN 1543-1894 Series E-ISSN 1940-6037

PALMY

Conductance of Correlated Nanostructuresity and affinity. These reagents therefore have long held promise as a means of influencing the growth and spread of malignant disease. Over a number of decades therapeutic antibodies have been developed either as single entities or conjugated to a variety of potential disease-ameliorating agents.