Titlebook: Developmental Toxicology; Methods and Protocol Craig Harris,Jason M. Hansen Book 2012 Springer Science+Business Media, LLC 2012 antioxidant

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书目名称Developmental Toxicology影响因子(影响力)




书目名称Developmental Toxicology影响因子(影响力)学科排名




书目名称Developmental Toxicology网络公开度




书目名称Developmental Toxicology网络公开度学科排名




书目名称Developmental Toxicology被引频次




书目名称Developmental Toxicology被引频次学科排名




书目名称Developmental Toxicology年度引用




书目名称Developmental Toxicology年度引用学科排名




书目名称Developmental Toxicology读者反馈




书目名称Developmental Toxicology读者反馈学科排名

phlegm

In Vivo Models of Developmental Toxicology,d at a sufficient dosage during a sensitive period of development in a sensitive species. While in vitro approaches in developmental toxicology can provide a means to assess the potency of toxicants, ultimately, the need to use whole animal models to demonstrate embryotoxicity is necessary to fully

决定性

, as a Model in Developmental Toxicology,ng with conservation of disease and stress response pathways, availability of mutant and transgenic strains, and wealth of biological information, have led to the increased use of . in toxicological studies. Although the potential to study the mechanisms of developmental toxicology in . is promising

Noctambulant

Zebrafish Embryo Developmental Toxicology Assay,y is approximately 87% in AB strain fish (Brannen KC et al., Birth Defects Res B Dev Reprod Toxicol 89:66–77, 2010). The procedure entails exposing dechorionated gastrulation-stage embryos to a range of compound concentrations for 5 days throughout embryonic and larva development. The larvae are eva

Neolithic

Gene Knockdown by Morpholino-Modified Oligonucleotides in the Zebrafish (,) Model: Applications forany advantages of zebrafish include their small size, prolific spawning, rapid development, and transparent embryos. They can be easily manipulated genetically through the use of transgenic technology and gene knockdown via morpholino-modified antisense oligonucleotides (MOs). Knocking down specific

缝纫

An Amphibian Model for Studies of Developmental Reproductive Toxicity,ces of early life-stage exposure to endocrine disrupting chemicals. The African clawed frog . has several characteristics which facilitates studies of developmental reproductive toxicity. Here, I present a . test protocol, including study design, exposure regime, and endpoints for chemical disruptio

缝纫

Avian Models in Teratology and Developmental Toxicology,plant culture. Like mammals, avian embryos have an allantois and their developmental pathways are highly conserved with those of mammals, thus avian models have biomedical relevance. Fertile eggs are inexpensive and the embryo develops rapidly, allowing for high-throughput. The chick genome is seque

liposuction

Primary Cell and Micromass Culture in Assessing Developmental Toxicity,of which was reproductive/developmental toxicity. Thousands of chemicals will need testing which will require a large number of laboratory animals. In vitro systems (as pre-screens or as validated alternatives) appear to be useful tools to reduce the number of whole animals used or refine procedures

degradation

Embryonic Stem Cell Test: Stem Cell Use in Predicting Developmental Cardiotoxicity and Osteotoxicit With appropriate toxicity data sets, acceptable exposure levels and actual safety of prescription and nonprescription drugs as well as environmental chemicals could be established for individuals that are more vulnerable to chemical exposure, such as pregnant women and their unborn children. The ga

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