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Titlebook: Developmental Toxicology; Keith Snell Book 1982 Keith Snell 1982 drug.environment.toxicology

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Vito Racanelli,Claudia Brunettihom they may be transmitted via the maternal circulation. The most overtly recognisable adverse effect of exposure to a toxicant in this manner is either intrauterine fetal death or birth of the fetus with anatomical malformations (see reviews by Wilson, 1973; Smithells, 1976). Tne identification of
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The Distribution of Drugs and Other Agents in the Fetus,re likely to cause their adverse effect directly in the fetus — in the tissues which are affected. Evidence for this is that a number of substances accumulate selectively in the critical fetal tissues.
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,Rechtsformübergreifende Entwicklungen,g. polyhalogenated biphenyls, methyl mercury, cigarette smoke, dioxins, etc.) likewise appear to be harmful to human embryos and fetuses. This recognition has also been a major factor in the increased attention to placental toxicology.
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Haftung für Gasversorgungsstörungenpossible embryopathic effects. A quartet of effects are relevant in this context; namely, fetal death (with consequent resorption or abortion), fetal malformation (true teratologies in the morphological sense) abnormalities of function (perhaps associated with faulty histogenesis) and intra-uterine growth retardation.
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