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Titlebook: Development and Recognition of the Transformed Cell; Mark I. Greene,Toshiyuki Hamaoka Book 1987 Plenum Press, New York 1987 biology.cell.c

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楼主: APL
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Two ,-Related Protooncogenes Encoding Growth Factor Receptors,. All these genes originated from genes carried by host cells, which were tentatively named cellular oncogenes or protooncogenes.. The remarkable conservation of protooncogenes over vast distances of evolutionary time. had led to the idea that protooncogenes play key roles in vital functions in orga
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The Receptor for Epidermal Growth Factor,-weight growth factor (.. 6000) can be isolated as a component of a high-molecular-weight complex with an associated arginine esterase activity. . EGF has been found in all mammals and, in humans, is a component of nearly all body fluids.. A variety of biological responses are mediated by EGF . and
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Protein Kinase C as the Site of Action of the Phorbol Ester Tumor Promoters,d cellular responses in mouse skin, of which increased cellular proliferation and hyperplasia are particularly prominent. In . systems likewise, the phorbol esters induce a wide spectrum of responses, including various alterations in cellular proliferation, differentiation, and intercellular communi
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Involvement of Human Retrovirus in Specific T-Cell Leukemia,ellular counterparts, and their significance in tumor development has been obtained from studies on retroviruses. Moreover, interest in oncogenes is now apparent in other fields of science, including developmental biology.
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Mechanisms of Virus-Induced Alterations of Expression of Class I Genes and Their Role on Tumorigeneayed in resistance to neoplasia. This fact has also been recently documented by numerous investigators.. Our early studies showed that resistance to RadLV-induced leukemia is mediated by a gene(s) in the .-. region of the major murine histocompatibility complex (MHC).. These experiments indicated a
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