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Titlebook: Degenerative Retinal Diseases; Matthew M. LaVail,Joe G. Hollyfield,Robert E. Ande Book 1997 Springer Science+Business Media New York 1997

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https://doi.org/10.1007/978-3-658-29967-5lental vascularized mass due to maldeveloped retina, followed by complications of cataracts and corneal opacities leading to bulbar atrophies in adult. Some patients have psychomotor retardation and progressive hearing loss as part of a multisystem syndromic disorder. This vitreoretinal dysplastic d
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Die polumschaltbaren Maschinen, (15-30%) in the age group of >75 years (Bressler., Klein., Vingerling., Mitchell.) will significantly increase, causing enormous social and financial problems for the community. In spite of the significance of the problem, to date the pathogenesis of AMD remains unknown and the disease is essential
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Die polumschaltbaren Maschinen,ntralis. Iodoacetate (IA) was administered by subretinal injection in the area centralis. Subretinal delivery involved injection of IA into the subretinal space of a 4 mm diameter retinal bleb, using a dose of 0.1, 1, 1.6, 2 or 5 µg IA/bleb. IA was dissolved in 50 µl of BSS or a viscous hyaluronate
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https://doi.org/10.1007/3-540-35017-9 inherited retinal dystrophies both in different animal species and in human. In dogs, different types of retinal dystrophies have been described affecting primarily the photoreceptors and/or pigment epithelium. A recessively inherited retinal dystrophy has been reported in a strain of Swedish Briar
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https://doi.org/10.1007/3-540-35017-9tic trait in autosomal recessive (ar), autosomal dominant (ad) and X-linked fashions. While it had long been suspected that RP initially involves the photoreceptor cells, it was not until defects in photoreceptor-specific gene products were identified in patients with adRP (2) or arRP (3,4) that thi
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https://doi.org/10.1007/978-3-322-98658-0s investigations, has long been considered to be the primary pathology leading to retinal degeneration in this mutant (1–3). Light microscopic and ultrastructural studies of the developing photoreceptors of these animals have determined that the phagocytic defect is first evident around postnatal da
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https://doi.org/10.1007/978-3-322-98658-0omeres of retinoid-deprived flies. In .. the visual system recovers quickly upon retinoid replacement even after prolonged deprivation. Importantly, photoreceptors do not degenerate. Total deprivation of all retinoids including retinoic acid is possible in . Thus deprivation of vitamin A chromophore
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