Titlebook: Damage-Associated Molecular Patterns in Human Diseases; Volume 3: Antigen-Re Walter Gottlieb Land Book 2023 The Editor(s) (if applicable) a

SPARK

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CRANK

ADJ

Virulence of Pathogens and the Counteracting Responses of the Host parasites, while the second part deals with the counteracting host defense responses against the various virulence factors, such as initiation of cell-autonomous stress responses and—if these defensive actions fail—the decision of cells to undergo regulated cell death as a prolific source of DAMPs

CRP743

AUGUR

吹牛者

Basic Trajectories in Autoimmunity mechanisms of central and peripheral T cell and B cell tolerance induction to self/self antigens. The centerpiece of this overview is the presentation of the danger/injury model of tolerance induction, which states that it is the responsibility of the peripheral bodily tissue, rather than the innat

吹牛者

上涨

DAMPs in Organ-Specific Autoimmune Diseaseso prototypical disorders of this group, multiple sclerosis and type 1 diabetes mellitus. The pathogenesis of both disorders is complex and orchestrated by an interrelationship between environmental triggers, genetic predisposition, and epigenetic modifications. In view of the danger/injury model and

BARB

Arteriography

Approaching the DAMPome: Evolution in Medicine?d that can be qualified as DAMPs or SAMPs, and the discoveries are far from over. Accordingly, the observations and findings about their chemical structure, nature, and function in biomedicine, as briefly addressed in this book, can only be considered as a “snapshot narrative.” This is all the more