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Titlebook: DNA Replication; From Old Principles Hisao Masai,Marco Foiani Book 2017 Springer Nature Singapore Pte Ltd. 2017 Replication origins.DNA re

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Termination of Eukaryotic Replication Forks, the first glimpse of the mechanism of replication fork termination. In this chapter I will summarise the recent findings on replication termination, weigh this against the past literature and discuss relevant consequences and views for the future.
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Roles of SUMO in Replication Initiation, Progression, and Termination,ter summarizes these new findings, and how they can integrate with the known regulatory circuitries of replication. As this area of research is still at its infancy, many outstanding questions remain to be explored, and we discuss these issues in light of the new advances.
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Rif1-Dependent Regulation of Genome Replication in Mammals,n normally all fire together? Is this important? And if so, why? Would any order of firing do, or does the specific sequence matter? How is this process regulated? These questions concern all eukaryotes but have proven extremely hard to address because replication timing is a process intricately connected with multiple aspects of nuclear function.
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Fazia Aboud,Nathalie Grangeon,Sylvie Norremination of the structure of the inactive double hexamer at an unprecedented resolution of 3.8 Å. This review will focus on the fine details observed in the Mcm2-7 double hexameric complex and their implications for the function of the Mcm2-7 hexamer in its different roles during DNA replication.
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Artificial General Intelligencectivity, and assembly of DNA-loaded protein complexes to license replication origins. In this chapter we describe these critical G. events necessary for DNA replication and their regulation in the context of both cell-cycle entry and cell-cycle progression.
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