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Titlebook: DNA Replication; From Old Principles Hisao Masai,Marco Foiani Book 2017 Springer Nature Singapore Pte Ltd. 2017 Replication origins.DNA re

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发表于 2025-3-21 18:13:20 | 显示全部楼层 |阅读模式
书目名称DNA Replication
副标题From Old Principles
编辑Hisao Masai,Marco Foiani
视频video
概述Presents a historical overview of eukaryotic DNA replication by one of the legendary scientists in the field.Reviews comprehensive compilation of the newest information on DNA replication.Approaches i
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: DNA Replication; From Old Principles Hisao Masai,Marco Foiani Book 2017 Springer Nature Singapore Pte Ltd. 2017 Replication origins.DNA re
描述.This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades. The book begins with a historical overview of the studies on eukaryotic DNA replication by Professor Thomas Kelly, a pioneer of the field. The following chapters include genome-wide studies of replication origins and initiation factor binding, as well as the timing of DNA replications, mechanisms of initiation, DNA chain elongation and termination of DNA replication, the structural basis of functions of protein complexes responsible for execution of DNA replication, cell cycle-dependent regulation of DNA replication, the nature of replication stress and cells’ strategy to deal with the stress, and finally how all these phenomena are interconnected to genome instability and development of various diseases. By reviewing the existing concepts ranging from the old principles to the newest ideas, the book gives readers an opportunity to learn how the classical replication principles are now being modified and new concepts
出版日期Book 2017
关键词Replication origins; DNA replication initiation factors: DnaA, ORC, MCM; Replication timing: TAD, LAD,
版次1
doihttps://doi.org/10.1007/978-981-10-6955-0
isbn_softcover978-981-13-4972-0
isbn_ebook978-981-10-6955-0Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightSpringer Nature Singapore Pte Ltd. 2017
The information of publication is updating

书目名称DNA Replication影响因子(影响力)




书目名称DNA Replication影响因子(影响力)学科排名




书目名称DNA Replication网络公开度




书目名称DNA Replication网络公开度学科排名




书目名称DNA Replication被引频次




书目名称DNA Replication被引频次学科排名




书目名称DNA Replication年度引用




书目名称DNA Replication年度引用学科排名




书目名称DNA Replication读者反馈




书目名称DNA Replication读者反馈学科排名




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发表于 2025-3-21 22:25:13 | 显示全部楼层
Structure of the MCM2-7 Double Hexamer and Its Implications for the Mechanistic Functions of the Mcmination of the structure of the inactive double hexamer at an unprecedented resolution of 3.8 Å. This review will focus on the fine details observed in the Mcm2-7 double hexameric complex and their implications for the function of the Mcm2-7 hexamer in its different roles during DNA replication.
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休战
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怒目而视
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发表于 2025-3-22 14:13:31 | 显示全部楼层
Laurence Moreau-Giraud,Pascal Lafondinated by the replication clamp PCNA and produces a regulated degradation of the RNA primer, thereby preventing the formation of long-strand displacement flaps. Occasional long flaps are further processed by backup nucleases including Dna2.
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发表于 2025-3-22 17:03:07 | 显示全部楼层
Fazia Aboud,Nathalie Grangeon,Sylvie Norre the first glimpse of the mechanism of replication fork termination. In this chapter I will summarise the recent findings on replication termination, weigh this against the past literature and discuss relevant consequences and views for the future.
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发表于 2025-3-23 00:59:27 | 显示全部楼层
Leonor Melo,Francisco Pereira,Ernesto Costa single particle electron microscopy and X-ray crystallography. These recent structural studies have outlined the overall architecture of a core replisome subassembly and shed new light on the mechanism of eukaryotic replication.
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发表于 2025-3-23 03:59:29 | 显示全部楼层
Artificial General Intelligenceter summarizes these new findings, and how they can integrate with the known regulatory circuitries of replication. As this area of research is still at its infancy, many outstanding questions remain to be explored, and we discuss these issues in light of the new advances.
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