Titlebook: DNA Repair and Mutagenesis in Eukaryotes; W. M. Generoso,M. D. Shelby,F. J. Serres Book 1980 Springer Science+Business Media New York 1980

审问

星球的光亮度

Isolation and Characterization of Repair-Deficient Mutants of ,s or leaky alleles of loci which have indispensable cellular functions. In several cases, both leaky and null alleles have been identified, indicating that at least some of these loci represent apparently dispensable cellular functions..The mutagen sensitivity of doubly-mutant . strains is being emp

BILIO

Patrimony

高度

Mutation Induction in Repair-Deficient Strains of Drosophilahe mutant .. was found to be unable to process lesions induced by the crosslinking agent nitrogen mustard (HN2) into point mutations (measured as sex-linked recessive lethals). Alkylation damage leads to increased point mutation frequencies in the excision repair deficient mutant .., but to reduced

Armory

拥挤前

Relationship of DNA Lesions and their Repair to Chromosomal Aberration Production aberration production in xeroderma pigmentosum cells had found them no more sensitive to mitomycin C than normal cells [50]. Similarly, Fanconi’s anemia cells, which are chromosomally sensitive to crosslinking agents, and appear to be defective in the “unhooking” of linked polynucleotide strands [1

BRAWL

Relationship of DNA Repair and Chromosome Aberrations to Potentially Lethal Damage Repair in X-Irradrepair, reaching a minimum level by 6 hr; this decrease correlated temporally with the repair of the slowly rejoining DNA strand breaks. The possible relationship of DNA repair to changes in survival and chromosome aberrations is discussed.

AORTA

DOTE

Book 1980entially lethal lesions at the expense of making mutations. The error-avoiding systems asso­ ciated with replication are themselves complex and may be caused to make mistakes in various ways. These different pathways for mutation production and mutation avoidance are still being worked out in prokar