| 书目名称 | DNA Recombination | | 副标题 | Methods and Protocol | | 编辑 | Hideo Tsubouchi | | 视频video | | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .Homologous recombination is important in various aspects of DNA metabolism, including damage repair, replication, telomere maintenance, and meiosis, and yeast genetics has successfully provided a framework for the mechanism of homologous recombination. Divided into four convenient sections, .DNA Recombination: Methods and Protocols. covers recent techniques that best utilize the advantages of the yeast system, prescribing to the belief that yeast will keep serving as a great model organism to study homologous recombination. Chapters have also been included for such exceptions as the group of genes involved in recombination that are found solely in higher eukaryotes, such as BRCA2. And looking forward, a necessary step in the direction of understanding the homologous recombination process is to isolate the machine and let it work in a test tube. Understanding the design by studying the appearance and behavior of the machinery as a single molecule will be an important milestone toward understanding the mechanism of action of the machinery. Techniques covering these topics have also been included. Written in the successful .Methods in Molecular Biology™. series format, chapters inc | | 出版日期 | Book 2011 | | 关键词 | DNA double-strand break; DNA microarrays; genome stability; higher eukaryotes; homologous recombination; | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-61779-129-1 | | isbn_softcover | 978-1-4939-5778-1 | | isbn_ebook | 978-1-61779-129-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC 2011 |
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发表于 2025-3-21 18:28:24
