书目名称 | DNA Modifications | 副标题 | Methods and Protocol | 编辑 | Alexey Ruzov,Martin Gering | 视频video | | 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | This book provides an overview of methods and experimental protocols that are currently used to analyze the presence and abundance of non-canonical DNA nucleotides in different biological systems. Focusing particularly on the newly discovered and less studied DNA modifications that are enzymatically produced and are likely to play specific roles in various biological processes, the volume explores chromatography- and mass spectrometry-based techniques for the detection and quantification of DNA modifications, antibody-based approaches to study their spatial distribution in different cells and tissues, and methods to analyze their genomic distribution with the help of bioinformatics tools that interrogate the corresponding datasets. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and comprehensive, .DNA Modifications: Methods and Protocols. serves as an ideal guide to research scientists and PhD students in this rapidly develop | 出版日期 | Book 2021 | 关键词 | Non-canonical DNA nucleotides; DNA demethylation; Mass Spectrometry; Antibody-based techniques; Bioinfor | 版次 | 1 | doi | https://doi.org/10.1007/978-1-0716-0876-0 | isbn_softcover | 978-1-0716-0878-4 | isbn_ebook | 978-1-0716-0876-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
The information of publication is updating
|
|