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Titlebook: DNA Damage and Repair in Human Tissues; Betsy M. Sutherland,Avril D. Woodhead Book 1990 Plenum Press, New York 1990 DNA.Laboratory.Xeroder

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https://doi.org/10.1007/978-1-4842-5750-0 treat patients with the erythrodermic form of CTCL (Edelson et al., 1987). In this treatment, a patient’s lymphocytes are extracorporeally irradiated with UVA in the presence of 8-methoxy-psoralen (8-MOP), and then are reinfused.
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Architecting Dependable Systems IIt of a population of stem cells that give rise to immunologically competent lymphoid cells. Although many questions need to be answered before we know the efficacy of such therapy, the National Institute of Health has issued guidelines for its use, and clinical trials have already begun (Culliton, 1989).
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DNA Damage and Repair in Human Skin: Pathways and Questionsvidual to repair a lesion, and (3) the strategy that skin employs to deal with the different spectra of lesions inflicted under varying environmental conditions. Thus, cellular responses to DNA damage, including repair of DNA lesions, are critical factors in determining the final level of damage and its consequences.
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Prospects for Epithelial Gene Therapyt of a population of stem cells that give rise to immunologically competent lymphoid cells. Although many questions need to be answered before we know the efficacy of such therapy, the National Institute of Health has issued guidelines for its use, and clinical trials have already begun (Culliton, 1989).
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5-MOP Induced Protection Against Epidermal DNA Damage by Ultraviolet Radiation in Human Skinn the incidence of skin cancers. It also seems reasonable to suppose that the possible depletion of the stratospheric ozone layer, over populated areas of the earth’s surface, would result in a further long-term increase of skin cancer (van der Leun, 1988).
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Repair of 8-MOP Photoadducts in Human Lymphocytes treat patients with the erythrodermic form of CTCL (Edelson et al., 1987). In this treatment, a patient’s lymphocytes are extracorporeally irradiated with UVA in the presence of 8-methoxy-psoralen (8-MOP), and then are reinfused.
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“Sie ist vieldeutig und autonom.”A does not have to be labeled with radionuclides or of a particular conformation, thus facilitating the use of the method in measuring damage levels and repair rates in the DNA of intact organisms -- including man.
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