Titlebook: DNA Binders and Related Subjects; Michael J. Waring,Jonathan B. Chaires Book 2005 Springer-Verlag Berlin Heidelberg 2005 DNA.Isomer.Nucleo

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Finanzmarktkapitalismus und Arbeitannot be unambiguously extracted from conventional X-ray diffraction experiments. We give several examples where incorrect atom-type assignments have been revealed by anomalous scattering experiments. Published structures and the database that contains them do not provide realistic representations o

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Structural Selectivity of Drug-Nucleic Acid Interactions Probed by Competition Dialysis,od, competition dialysis has been used worldwide to probe a variety of ligand-nucleic acid interactions. This chapter will focus on new analytical approaches for extracting information from the database that resulted from the first-generation competition dialysis assay, in which binding data were ga

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Between Objectivity and Whim: Nucleic Acid Structural Biology,annot be unambiguously extracted from conventional X-ray diffraction experiments. We give several examples where incorrect atom-type assignments have been revealed by anomalous scattering experiments. Published structures and the database that contains them do not provide realistic representations o

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Topoisomerase Inhibitors of Marine Origin and Their Potential Use as Anticancer Agents,somerase I have also been discovered such as wakayin, kalihinol F, and the cyclic peptide sansalvamide A, which inhibits the type I topoisomerase from the . virus. But the leading topoisomerase I poison is the marine alkaloid lamellarin D, recently characterized as a potent pro-apoptotic cytotoxic a

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DNA Major Groove Binders: Triple Helix-Forming Oligonucleotides, Triple Helix-Specific DNA Ligands velopment of triple helix-forming oligonucleotides as highly sequence-specific DNA major groove binders, the related triple helix structures, examples of triple helix-specific ligands and DNA cleaving agents, as well as their biological relevance, during the last 10–15 years.

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