Titlebook: DNA Binders and Related Subjects; Michael J. Waring,Jonathan B. Chaires Book 2005 Springer-Verlag Berlin Heidelberg 2005 DNA.Isomer.Nucleo

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Telekooperation im Top-Managementod is based on firm thermodynamic principles and is simple to implement. In the competition dialysis experiment, an array of nucleic acid structures and sequences is dialyzed against a common test ligand solution. After equilibration, the amount of ligand bound to each structure or sequence is deter

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Finanzmarktkapitalismus und Arbeitecules, monovalent and divalent cations, and polyamines compete for similar or adjacent sites. Many of these species give identical electron distributions (electron density maps). Such scattering iso-types allow one to construct different models that give similar fits of model to data. Even models w

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Thomas Haipeter,Christine Slomkaisomerases. These enzymes that resolve DNA topological constraints in cells are the primary targets for a large diversity of natural products extracted from plants, microorganisms or, as reviewed here, from marine organisms. Marine products capable of stabilizing topoisomerase II-DNA covalent comple

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Thomas Haipeter,Christine Slomkaimportant signals for regulating gene expression, and for maintaining genome integrity and stability. The design of tailor-made molecules that recognize specific sequences in the DNA double helix would provide interesting tools to interfere with DNA information processing and to target genome modifi

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Der Gestaltwandel des Mittelstandes990–2000) saw a resurgence in aminoglycoside-based drug development as their chemistry/mechanism of action became better understood. This work, however, had almost exclusively focused on targeting RNA. This review summarizes new developments (past 4–5 years) in aminoglycoside–nucleic acid interactio

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Der Gestaltwandel des Mittelstandesntibiotic activities are ascribed to their abilities to bind a highly conserved sequence (termed the A site) in the 16S rRNA of the 30S ribosomal subunit and interfere with protein synthesis. The aminoglycosides represent a paradigm for both drug–RNA and drug–ribosome interactions, and information g

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https://doi.org/10.1007/b99428DNA; Isomer; Nucleotide; RNA; biochemistry; gene expression; glycosides; nucleotides

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