| 书目名称 | DJ-1/PARK7 Protein | | 副标题 | Parkinson’s Disease, | | 编辑 | Hiroyoshi Ariga,Sanae‘M. M. Iguchi-Ariga | | 视频video | | | 概述 | Covers various oxidative stress-related diseases, including cancer, neurodegenerative diseases, and type 2 diabetes as well as male infertility.Broadens the understanding of the various uses of DJ-1 s | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. The .DJ-1 .gene was first found to be a novel oncogene in 1997 and later, in 2003, also found to be a causative gene for a familial form of Parkinson’s disease (PD), park7. The .DJ-1. gene is therefore the first gene discovered that is known to cause cancer and neurodenegerative diseases, including PD. The research field has expanded as the research has developed. Thus this volume begins with a general introduction of .DJ-1., and explains the history and research development to understand the following chapters. Those chapters present the roles of .DJ-1. in various oxidative stress-related diseases such as neurodegenerative diseases, as well as cancer, diabetes, and fertility. Moreover, several chapters present evidence that DJ-1 is useful for therapeutic strategies against these diseases. The reader willdiscover that DJ-1 is a promising protein both for basic cell biology and for the mechanism and therapy for oxidative stress-related diseases. . | | 出版日期 | Book 2017 | | 关键词 | DJ-1; Parkinson’s disease; Cancer; Type 2 diabetes; Male infertility; Oxidative stress; Mitochondria; Signa | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-10-6583-5 | | isbn_softcover | 978-981-13-4908-9 | | isbn_ebook | 978-981-10-6583-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | Springer Nature Singapore Pte Ltd. 2017 |
The information of publication is updating
|
|
发表于 2025-3-21 20:07:38
