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Titlebook: Cytokines: Interleukins and Their Receptors; Razelle Kurzrock,Moshe Talpaz Book 1995 Kluwer Academic Publishers 1995 cytokine.cytokines.on

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https://doi.org/10.1007/978-3-476-03745-9me receptor, and possess identical biological activities [21,22]. In contrast to the agonist activities of IL-1α and IL-1β, IL-1RA is a specific antagonist of IL-1 that acts by blocking the binding of IL-1 to its cell surface receptors [23–25].
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Interleukin-1 and its inhibitors: Implications for disease biology and therapy,me receptor, and possess identical biological activities [21,22]. In contrast to the agonist activities of IL-1α and IL-1β, IL-1RA is a specific antagonist of IL-1 that acts by blocking the binding of IL-1 to its cell surface receptors [23–25].
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Interleukin-7 and lymphopoiesis: Biological and clinical implications,ion, IL-7 appears to hold promise in enhancing antimicrobial responses. This chapter describes in detail the current status of IL-7 as a regulator of lymphopoiesis and effector cell function, and the potential therapeutic implications of the IL-7 preclinical studies performed in mice.
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Interleukin-3 and its receptor,em and to direct it to specific targets [1], Among these, IL-3 (or multi-CSF) is known as a pleiotropic cytokine with a broad spectrum of target cells and functions. This article summarizes relevant data about this molecule that has been the topic of several recent review articles [2–5].
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Interleukin-6: A comprehensive review,ent progress in the analysis of IL-6-activated signal transduction mechanisms. IL-6 expression in different disease states has been demonstrated; IL-6 may be involved as a mediator in certain aspects in the pathogenesis of infection, autoimmunity, and malignancy.
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Control of thrombocytopoiesis: Current state of the art,elet production.[1] The cells of the megakaryocyte lineage include the primitive, actively proliferating progenitors cells as well as mature post-mitotic megakaryocytes undergoing maturational development (Figure 1). The complex nature of this developmental hierarchy is underscored by the wide varie
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