Titlebook: Cytokine Yearbook Volume 1; An Official Publicat S. Pestka,H. Schellekens,P. Wussow Book 1996 Kluwer Academic Publishers 1996 cytokine.cyto

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Type I interferon genes and proteins,rons, or by different spatial or temporal patterns of expression. Different functions would require different receptors for each interferon, while different patterns of expression would require different transcriptional or postranscriptional regulatory mechanisms. It is also necessary to explain whe

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Interferon receptors,cal responses. These effects include antiviral and antiproliferative activity, stimulation of cytotoxic activity in lymphocytes, natural killer cells and macrophages, modulation of cellular differentiation and stimulation of class I MHC antigens and other surface markers [67, 90]. Like most cytokine

Inertia

Schlemms-Canal

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Biological effects of the interferons and other cytokines,ractory state in the reponse to interferon (IFNs) and antibodies in treated patients; Workshop 7, IFNs, multiple sclerosis, and the nervous system; Workshop 9, Viral inhibition of the response to IFNs and other cytokines; Workshop 10, Cell growth inhibition by IFNs and other cytokines; Workshop 12,

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考得

Oral application of cytokines,f the studies suggested that orally or nasally administered interferons exerted their antiviral activity locally [Cummins and Hutcheson, 1983; Cummins and Rosenquist, 1980; Greenberg .., 1978; Hayden .., 1986; Higgins .., 1983; Merigan .., 1973; Schafer .., 1972; Smith .., 1987; Turner .., 1986]. Mo

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Interferons and the tumor cell,ted out three modes of such actions relevant for the antitumor efficacy exerted by IFNs: effects on apoptosis, effects on genes involved in malignant transformation and effects on angiogenesis. These are but three selected areas forming a basis for the development of optimal IFN therapy. Further exp

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Cytokines and bacterial infections,ions caused by nonviral agents, including a wide range of bacteria. Cytokines can be major mediators of the pathogenic effect in some diseases, and represent important defense mechanisms in others. Detailed knowledge on the role of the growing number of recognised cytokines is important, because it

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