Titlebook: Cytochrome P450; In Vitro Methods and Zhengyin Yan,Gary W. Caldwell Book 2021 The Editor(s) (if applicable) and The Author(s), under exclus

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Yiming Yuan,Zhenkun Yan,Xuan Lian also play a similar role in the metabolism of drugs and other xenobiotics. Oftentimes, CYPs and non-CYP enzymes can share substrate specificity and collectively catalyze oxidative metabolic reactions of the same drug. Therefore, it is of importance in drug discovery to differentiate CYP-mediated

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https://doi.org/10.1007/978-1-0716-1542-3Drug candidates; Therapeutic targets; CYP enzymes; Drug metabolites; Drug discovery and development; Meta

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978-1-0716-1544-7The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines

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Annuaire Européen / European Yearbookvery. Chapter . provides comprehensive information concerning CYP enzymes and their related metabolism properties on xenobiotics, while Chapters .–. provide detailed CYP and non-CYP in vitro methods and protocols that can be easily established in a drug discovery pipeline.

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