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Titlebook: Computational Methods in Systems Biology; 22nd International C Roberta Gori,Paolo Milazzo,Mirco Tribastone Conference proceedings 2024 The

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,Reverse Engineering of Renal Tubule Networks in the High-Dimensional Regime,ology. New developments in protein mass spectrometry have resulted in a marked increase in sensitivity of protein detection and quantification. In order to address this problem, we developed an algorithm rooted on Graphical Gaussian Models to infer a network, and on a simple method to establish the
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Deciphering Structural Selective Constraints: A Comparative Evolutionary Analysis of RNA Hairpin Stnges. We evaluate evidence of structural selective constraint by quantifying the destabilization of hairpin structures in its absence. Our analysis reveals significantly higher rates of double compensatory base-pair substitutions in functional hairpins than expected. Additionally, we observe signifi
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,Uncovering Dynamic Structures Within Cyclic Attractors of Asynchronous Boolean Networks with Spectrin which a system remains for a long time before it switches to another metastable set. As a proof-of-concept, we apply this method to Boolean models of the mammalian cell cycle. By considering the categorization of transitions as either slow or fast, we investigate the impact of time information on
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