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Titlebook: Computational Methods in Systems Biology; 22nd International C Roberta Gori,Paolo Milazzo,Mirco Tribastone Conference proceedings 2024 The

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,Approximate Reductions of Rational Dynamical Systems in CLUE,ger aggregating power at the expense of a bounded error. Additionally, our extension includes new functionalities such as an interface to the model database ODEBase repository and simulation techniques for exploratory analyses.
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https://doi.org/10.1007/978-3-658-19706-3ity) properties, and model checking temporal (LTL and CTL) formulas for our extended RSs. We analyze a breast cancer case study and show that our model checking analyses can in some cases improve the administration of monoclonal antibodies therapeutic treatments.
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,Process Calculi and Rewriting Techniques for Analyzing Reaction Systems,ity) properties, and model checking temporal (LTL and CTL) formulas for our extended RSs. We analyze a breast cancer case study and show that our model checking analyses can in some cases improve the administration of monoclonal antibodies therapeutic treatments.
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Conference proceedings 2024ta-based approaches for systems and synthetic biology; optimality and control of biological systems; modeling, analysis, and control of microbial communities. The conference welcomes new theoretical results with potential applications to systems and synthetic biology, as well as novel applications a
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,Graphical Conditions Ensuring Equality Between Differential and Mean Stochastic Dynamics,larly that the mean of the CTMC trajectories is equal to the solution of the ODE at all time points. In this paper, we generalize that result in presence of polyreactant reactions, by introducing the Stoichiometric Influence and Modification Graph (SIMG) of an RS, and by showing that the equality be
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,Computing Thermodynamically Consistent Elementary Flux Modes with Answer Set Programming,cle, we have added thermodynamic constraints in terms of the Gibbs energy of reactions, which constrain metabolite concentrations within a chosen interval. This constraint is added as a theory propagator and it reduces the enumeration during the computation. We applied our tool to the central carbon
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