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Titlebook: Cyclic Nucleotides; Part I: Biochemistry J. A. Nathanson,J. W. Kebabian Book 1982 Springer-Verlag Berlin Heidelberg 1982 Calcium.Nucleotide

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Guanylate Cyclase: Regulation of Cyclic GMP Metabolismate cyclase and cyclic GMP levels are sensitive to oxidizing and reducing agents in incubations, and hormone effects on this system may be mediated through alterations in the redox state of preparations. Increases in cyclic GMP levels in intact cells with nitro compounds are not dependent upon calci
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Cyclic Nucleotide Phosphodiesterasese. The phosphodiesterases isolated from various tissues differ in their substrate specificities, in their substrate affinities, and in their sensitivity to a variety of natural and artificial effectors. This variability has been observed even among the enzymes isolated from a single tissue. In fact,
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Immunocytochemistry of Cyclic Nucleotides and Their Kinases antisera are screened for their specificity by immunodiffusion and immunoprecipita-tion techniques..Antisera toward R., R., and C subunit have shown complete identity for their respective subunit or holoenzyme containing the subunit; crossreactivity against other subunits and holoenzyme has not bee
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Protein Phosphorylation: An Overview in regulation of carbohydrate metabolism, but also in regulation of some of the molecular processes underlying synaptic transmission, and possibly of other physiological processes occurring in the nervous system as well. For these reasons we proposed the hypothesis (K. and G. 1969), shown in Fig. 1
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Photoaffinity Labeling of Cyclic AMP-Dependent and Cyclic GMP-Dependent Protein Kinasesrotein kinases are the only proteins present in all tissues studied which are specifically labeled by 8-N.-cAMP. Other minor labeled proteins appear to be proteolytic fragments of the two types of regulatory subunits. The finding that most, if not all, specific cAMP-receptor proteins are regulatory
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