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Titlebook: Cyclic AMP, Cell Growth, and the Immune Response; Proceedings of the S Werner Braun,Lawrence M. Lichtenstein,Charles W. P Conference procee

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书目名称Cyclic AMP, Cell Growth, and the Immune Response
副标题Proceedings of the S
编辑Werner Braun,Lawrence M. Lichtenstein,Charles W. P
视频videohttp://file.papertrans.cn/242/241975/241975.mp4
图书封面Titlebook: Cyclic AMP, Cell Growth, and the Immune Response; Proceedings of the S Werner Braun,Lawrence M. Lichtenstein,Charles W. P Conference procee
描述The brilliant research of Dr. Earl Sutherland and his colleagues has had a broad impact on many areas of biology. Among the fields in­ fluenced rather late by the insights arising from this work were im­ munology and oncology. Although research relating cyclic AMP metabol­ ism to the development and manifestations of the immune response and the control of mammalian cell growth is relatively recent, the growth of knowledge in these areas has been rapid and there is already a considera­ ble amount of empirical information. This conference provided an oppor­ tunity to collate and begin to interpret that information. A deliberate at­ tempt was made to bring together investigators nominally involved in im­ munology, biochemistry, pharmacology, or cellular biology for in many instances parallel observations are being obtained in these fields. For ex­ ample, the immunologist studying the transformation of lymphocytes by antigens or mitogens is carrying out experiments that are very close to those of the biologist studying the growth of cells in culture; in both cases, the phenomena they observe are modulated by changes in the in­ tracellular level of cyclic nucleotides. Many other example
出版日期Conference proceedings 1974
关键词Cell; antigen; immune response; lymphocytes; pharmacology
版次1
doihttps://doi.org/10.1007/978-3-642-86026-3
isbn_softcover978-3-642-86028-7
isbn_ebook978-3-642-86026-3
copyrightSpringer-Verlag Berlin Heidelberg 1974
The information of publication is updating

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Cyclic AMP in the Activation of Human Peripheral Blood Lymphocytes in Immunologically Deficient Patduced lymphocyte activation have consistently demonstrated suppression of macromolecular synthesis in the presence of exogenously administered cAMP or related compounds (Smith et al., 1971a). This occurs despite a demonstrated elevation of intracellular cAMP levels in lymphocytes following exposure
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Effects of Adenyl Cyclase-Stimulating Factors of Vibrio Cholerae on Antibody Formation,re biochemical events within lymphoid cells, some of which are related to the energy processes required to drive the cellular metabolism, and some of which are probably related to the reception and transmission of the antigenic signal itself. Adjuvants may act by influencing any or all of these inte
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Hormonal Control of the Immunologic Release of Histamine and Slow-Reacting Substance of Anaphylaxis as for IgE antibody. Although the hormones noted above can themselves stimulate secretion in some tissues, in the reaction to be considered, they modulate the secretory process stimulated by antigen-antibody interaction, instead.
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,Modulation of Cytotoxic T Lymphocyte Function by Cyclic 3′,5′-Mononucleotides,hether the cytotoxic lymphocytes are the same effector cells as those responsible for lymphokine secretion. The nature of the cytotoxic process is enigmatic; however, it may be mediated in part via synthesis and secretion of cytotoxic lymphokines (i. e., lymphotoxin) (Ruddle and Waksman, 1967).
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Werner Braun,Lawrence M. Lichtenstein,Charles W. P
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Automobile Engines and Car Electronicsor the activation of immunocompetent cells and for the regulation of the magnitude of their response. While adjuvant effects and tolerogenic effects have been familiar and widely investigated phenomena for a long time and are known to involve the same cells (14), we have only just begun to understan
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