Titlebook: Cutaneous Melanoma; Charles M. Balch,Michael B. Atkins,Arthur J. Sober Reference work 2020Latest edition Springer Nature Switzerland AG 20

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Clinical Epidemiology of Melanomae. The principal environmental risk factor for cutaneous melanoma is solar ultraviolet radiation, although the association is nonlinear and modified by host factors. While overall, fair-skinned populations residing in regions of high ambient insolation have higher rates of melanoma than those residi

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Clinical Genetics and Risk Assessment of Melanoma the last 10 years. Although sun exposure is still a significant environmental risk factor, the role of genes involved in skin pigmentation, nevus counts, telomere biology, and DNA repair as well as others has become more evident. Pigmentation genes have functions also in energy expenditure and immu

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Studies in Professional Life and Workhis chapter, we will describe important considerations when performing a biopsy of a lesion suspicious for melanoma, commonly used biopsy techniques, and their applications to maximize biopsy accuracy in the initial diagnosis of melanoma.

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Classification and Histopathology of Melanomalogic, pathologic, and molecular features have been integrated to define nine pathways of melanoma pathogenesis. Recent molecular studies have also opened new avenues for the treatment of patients with metastatic melanoma, and molecular pathology is likely to play an important role in the expanding field of personalized melanoma therapy.

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outcomes of more than 70,000 patients.Includes supplementary.Written by the leading melanoma experts from the United States, Australia, and Europe, this new edition incorporates the clinical outcomes of more than 70,000 patients treated at major melanoma centers throughout the world and is the defin