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Titlebook: Cushing’s Syndrome; Lewis S. Blevins (Associate Professor of Medicine Book 2002 Springer Science+Business Media New York 2002 ACTH.hormon

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Aberrant Hormone Receptors,nomous.” Studies by several groups have now revealed that some of the cortisol-producing adrenal tumors or hyperplasias may actually be under the control of aberrant (or ectopic, illicit, or hyperactive) hormone membrane receptors. This chapter will focus on . and . evidences of the abnormal express
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,Transsphenoidal Surgery for Cushing’s Disease, disease (CD). Cure rates following surgery range from 20–90%, depending upon the institution, the accuracy of the pro-operative diagnosis, and the experience of the surgeon. Although diagnostic methods for defining a pituitary adenoma have improved in the past several decades, there remain challeng
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A Code for Carolyn: A Genomic Thrillerelopment, the central nervous system, and the adrenal medulla. Glucocorticoid secretion is regulated by hormonal interactions among the hypothalamus, pituitary, and adrenal cortex (HPA). The synthesis and secretion of cortisol, the most important glucocorticoid in humans, is regulated by adrenocorti
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https://doi.org/10.1007/978-94-015-3423-9gardless of aetiology, is a constellation of clinical and biochemical abnormalities resulting from chronic excess of cortisol. While there are classical features of Cushing’s syndrome, the diagnosis is increasingly being made earlier, before major complications have occurred. An early diagnosis is o
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https://doi.org/10.1007/978-4-431-68391-9lts from chronic exposure to excessive concentrations of glucocorticoids. The physical features of Cushing’s syndrome include weight gain, central obesity (., accumulation of adipose tissue in the facial, nuchal, truncal and girdle areas), facial plethora, hirsutism, cutaneous striae, muscle wasting
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Indications and Contraindications, mania and death.” In particular, Osler was impressed by the rapid weight gain and the “bloated” appearance of his patient’s face. Unfortunately, however, the constellation of symptoms and signs that we now attribute to glucocorticoid excess had not been described and the patient succumbed while be
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