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Titlebook: Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung; Volume 62 W. Arber,R. Haas,E. Wecker

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书目名称Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung
副标题Volume 62
编辑W. Arber,R. Haas,E. Wecker
视频video
丛书名称Current Topics in Microbiology and Immunology
图书封面Titlebook: Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung; Volume 62 W. Arber,R. Haas,E. Wecker
描述General aspects of nucleic acid uptake by mammalian cells have been the subject of several reviews during the last few years (PAGANO, 1970; BHARGAVA and SHANMUGAM, 1971; DUBES, 1971; RYSER, 1967). These reviews covered methods used for the infection of cells by viral nucleic acids as well as interaction of mammalian cells with non-viral nucleic acids. This article is restricted to a discussion of experiments with poliovirus RNA and focuses special attention on the steps following the uptake of RNA into a cell, aspects that were not discussed in earlier review articles. The fate of input RNA once inside the cell is determined by the host cell but experimental conditions can be chosen to favor the survival of input RNA and the induction of a virus growth cycle by interfering with host-cell meta­ bolism through events that, in the case of infection with intact virus, might be controlled by viral proteins.
出版日期Conference proceedings 1973
关键词Immunität; RNA; biology; cell; growth; immunology; infection; microbiology; protein; proteins; virus
版次1
doihttps://doi.org/10.1007/978-3-642-65772-6
isbn_softcover978-3-642-65774-0
isbn_ebook978-3-642-65772-6Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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https://doi.org/10.1007/978-3-642-59915-6he infectivity of TMV-RNA, an observation that has since been made for a large number of other plant viruses. Transfection of animal cells by animal virus RNA and DNA has been demonstrated. Bacteriophage nucleic acids isolated from various RNA and DNA phages could be made infective for bacteria. All
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Immunological Recognition of Polynucleotide Structure,n provided. Although the overall geometry is thus right-handed helical, a variety of geometrically distinct forms are known to exist, for example the A, B and C forms of DNA and the A form of double-helical RNA. In addition, chemical and physical studies have shown that synthetic polynucleotide comp
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978-3-642-65774-0The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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