书目名称 | Current Topics in Complement II |
编辑 | John D. Lambris |
视频video | |
概述 | Proceedings from the Fourth Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics (June 10-15, 2007) |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | .Complement has long been regarded as a pivotal effector arm of the innate immune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or Inflammation. Several studies indicate that complement proteins exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system. The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led complementologists to revisit established biological systems, such as the complement system, from a global and integrative perspective. Complement research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory circu |
出版日期 | Book 2008 |
关键词 | autoimmune disease; bacteria; physiology; protein; virus; infectious diseases |
版次 | 1 |
doi | https://doi.org/10.1007/978-0-387-78952-1 |
isbn_softcover | 978-1-4419-2706-4 |
isbn_ebook | 978-0-387-78952-1Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |