Titlebook: Current Controversies in Bone Marrow Transplantation; Brian J. Bolwell (Director, Staff Physician) Book 2000 Humana Press Inc. 2000 blood.

APO

Carmen Colitz,Fabiano Montiani-Ferreiraute leukemia induced complete remission (CR) in the majority of patients, but postremission therapy was inadequate to prevent relapse .. Relapsed patients, and those who failed to achieve CR, invariably died from their leukemia.

ferment

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Additional Psychocultural ThemesGenerally, eligibility includes patients less than 55, 60, or 65 yr of age. Many autologous BMT (ABMT) protocols also have age cutoffs restricting patient eligibility. The reason for such an age cutoff is presumably that the transplant procedure itself is prohibitively risky in older patients. Commo

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Additional Psychocultural Themesowever, this approach has been limited by the availability of suitable human leukocyte antigen (HLA)-matched related donors, and by the occurrence of severe graft-vs-host disease (GVHD) when bone marrow (BM) from HLA-matched unrelated donor (MUD), or partially HLA-mismatched family member grafts, ar

Moderate

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Jong-Hwa Chun,Jang-Jun Bahk,In-Kwon Umengraftment unless the donor is syngeneic or the recipient is profoundly immunoincompetent. When BMT is performed for malignant disease, treatment of the recipient to permit engraftment is also used to eliminate residual malignancy. The ultimate success of allo-BMT for leukemia clearly depends upon

mercenary

Martin Torvald Hovland,Srikumar Royd to CML is 1.5/ 100,000/yr .. CML is characterized by a specific chromosomal abnormality referred to as the Philadelphia chromosome (Ph.) .,.. The Ph. results from the reciprocal translocation of the . proto-oncogene on the long arm of chromosome 9 (g34.1) to the 5.8 kb breakpoint cluster region (b

殖民地

Blasphemy

灾祸

Heritability of Aggressive Behavior,of the eradication of leukemia by high-dose chemotherapy (CT), stem cells previously collected, either in remission or at time of active disease, will almost certainly be contaminated by a population of tumor cells. Viable cells will logically result in relapse. If, however, there are no viable tumo