Titlebook: Critical Issues in Head and Neck Oncology; Key Concepts from th Jan B. Vermorken,Volker Budach,Brian O‘Sullivan Book 2018 Springer Nature S

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HPV Assessment in Oropharynx Cancer: What is the Gold Standard?s (HNSCCs), especially those arising from the oropharynx. HPV-associated oropharyngeal carcinomas (OSCCs) represent a clinically distinct form of HNSCC with a different clinical profile, prognosis, and therapeutic options than HPV-non-related HNSCC. Most importantly, the accurate diagnosis of HPV ca

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Can We Expect Less Toxicities with Newer Forms of Radiotherapy?and neck cancers are particularly difficult to treat and adverse effects like xerostomia and dysphagia are common. The major objective of radiation therapy has always been to achieve the best oncological outcome in terms of tumor control, while limiting side effects of cancer treatment. In the last

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ges to guidelines, minimum datasets and the revised WHO classification are discussed. Molecular sequencing has shed new light onto the subtype classification of head and neck cancer, and has also revealed marked heterogeneity between the immunological characteristics of head and neck and other cance

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lops in a single tissue in a relatively small anatomical region, it is remarkably heterogeneous. At present two separate disease entities are distinguished: HNSCCs caused by human papillomavirus (HPV) infection and those that do not contain HPV. However, multiple high-throughput biomolecular methods

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