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Titlebook: Coxsackieviruses; A General Update Mauro Bendinelli,Herman Friedman Book 1988 Springer Science+Business Media New York 1988 Antigen.Pathoge

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hout the world. Depending on virus type and factors such as age at infection, they may cause a wide spectrum of clinical diseases, including aseptic meningitis, common colds, epidemic myalgia (Bornholm disease), myocarditis, herpangina, pharyngitis, conjunctivitis, hand-foot-and-mouth disease, and p
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the recognized enteroviruses. Recent interest in the molecular biology of the CVB group reflects the growing realization that the CVBs probably are involved in important human diseases such as myocarditis. and have been implicated as putative causative agents in a variety of other diseases, such as
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syndromes, including meningitis, pleurodynia, myositis, herpangina, myocarditis, pericarditis, pancreatitis, hepatitis, nephritis, orchitis, gastroenteritis, exanthems, acute respiratory disease, and congenitally acquired disease. In addition, inapparent or mild infections may be common and provide
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iven variant to its pathogenicity in cell cultures or in animal models. In reading about studies about a particular variant, one must remember that any virus stock represents a genotypically heterogeneous population from which phenotypic expression of a dominant variant(s) is observed and measured.
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