| 书目名称 | Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium | | 编辑 | Rudolf Toman,Robert A. Heinzen,Jean-Louis Mege | | 视频video | | | 概述 | Provides the reader interesting insights into highly infectious intracellular pathogen Coxiella burnetii, the causative agent of Q fever, summarized by several leading groups in the field.Includes the | | 图书封面 |  | | 描述 | Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to thrive in the most inhospitable of cellular compartments-the phagolysosome. Understanding how C. burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen. Several chapters survey immune functions that control or potentially exacerbate Coxiella infection and delve into correlates of protective immunity elicited by vaccination. Comparative genomics is also the foundation of chapters discussing diagnostic antigen discovery and molecular typing of the bacterium, with significance for development of new clinical, epidemiologic, and forensic tools. | | 出版日期 | Book 2012 | | 关键词 | Coxiella burnetii; Developmental biology; Host-pathogen interactions; Immune evasion/modulation; Q fever | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-007-4315-1 | | isbn_softcover | 978-94-007-9205-0 | | isbn_ebook | 978-94-007-4315-1 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 201 |
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发表于 2025-3-21 16:28:35
