Titlebook: Cortical Development; Neural Diversity and Ryoichiro Kageyama,Tetsuo Yamamori Book 2013 Springer Japan 2013 Cortical development.Neural pro

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https://doi.org/10.1007/978-3-319-58353-2ust migrate over long distances following discrete pathways to reach the appropriate cortical areas. Thus, proper coordination of the distinct migration programs followed by pyramidal cells and interneuron precursors during development is crucial for the assembly of functional microcircuits within t

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https://doi.org/10.1007/978-3-319-58353-2 is the site of higher brain function. It contains two primary types of neurons: glutamatergic neurons (70–80 %) and GABA (γ-aminobutyric acid)-ergic neurons (20–30 %). Glutamatergic neurons release glutamate as neurotransmitter, which elicits excitation in the postsynaptic neuron, and are the princ

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Insects Today and in the Future,ayer 5. We have characterized highly selective synaptic connectivity among and between these pyramidal cell populations, which likely contributes to their establishing and maintaining functional loops between the frontal cortex, basal ganglia, and thalamus. However, less is known about how GABAergic

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Nima TaheriNejad,David Pollreisze in cerebellar Purkinje cell (PC) synapse formation. We found that a significant number of PC spines lack synaptic contacts with parallel fiber (PF) terminals and some of residual PF-PC synapses show mismatching between pre- and postsynaptic specializations in conventional and conditional GluRδ2 kn

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Mathieu Bagot,Pascale Launay,Frédéric Guideche mid-embryonic stage (embryonic day 83) when the thalamocortical fibers are about to project. In addition, . only shows weak activity-dependent expression upon monocular inhibition by TTX injection into one eye compared with other V1-selective genes. These findings suggest that there are at least

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Dynamic Notch Signaling in Neural Progenitor Cells,Dll1), which activate Notch signaling in neighboring cells. Activation of Notch signaling induces the expression of Hes1 and Hes5, which repress proneural gene expression, thereby maintaining neural progenitor cells. Thus, differentiating neurons keep their neighbors undifferentiated. Interestingly,

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Proneural Proteins and the Development of the Cerebral Cortex,r multiple roles in development of the mammalian cerebral cortex. The first part of the chapter considers the different aspects of telencephalic development that are regulated by proneural proteins, including the neuronal versus glial fate decision, the specification of glutamatergic and GABAergic n

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The Role of the Transcription Factor Pax6 in Brain Development and Evolution: Evidence and Hypothesiption factor Pax6 demarcates the dorsal telencephalon, thereby patterning the future cortical primordium. Pax6 is also crucial in neurogenesis in the developing cortex through its role in balancing proliferation and differentiation of neural progenitor cells (NPCs). In this chapter, we address the