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Titlebook: Correlation-based network analysis of cancer metabolism; A new systems biolog Emily G. Armitage,Helen L. Kotze,Kaye J. Williams Book 2014 T

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楼主: Sparkle
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Rajasekhar Batchu,Naran M. Pindoriya062, 2009; Semenza Trends Pharmacol Sci 33(4):207–214, 2012). However, simply developing antagonists to the HIF pathway is not enough as it is not yet established that HIF drives the transformation of a normal cell to a cancer cell (Esteban and Maxwell Nat Med 11(10):1047–1048, 2005).
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Web Technologies and Applicationsch as the proteome, transcriptome and genome. For many diseases including cancer, studying the metabolome enables us to gain a better understanding of global biological response of cancer cells in the progression of the disease. Revealing the complexity of the metabolome is particularly advantageous
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Tao Ge,Wenzhe Pei,Baobao Chang,Zhifang Suig oxygen homeostasis, such that the need for oxygen during oxidative phosphorylation and other metabolic reactions is balanced with the risk of oxidative damage within the cell, as reported by Ruan et al. (J Cell Biochem 107(6), 1053–1062, 2009). Hypoxia is the intermediate state between the homeost
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Is There a Cosmic Web of Life?,ogy for describing causality in biological systems. Ever since the 1920s, causation has been connected with correlation in this way. The underlying mechanisms in biological processes are shadowed in correlations that when analysed can reveal connections in biological data that provide a starting poi
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Rajasekhar Batchu,Naran M. Pindoriya07(6):1053–1062, 2009), thus they play a critical role in tumour survival and defence against eradication. Our knowledge and understanding of the mechanisms of HIFs have started to illustrate great scope in designing and screening of new anticancer therapies (Ruan et al. J Cell Biochem 107(6):1053–1
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Alexandros Kleidaras,Aristides Kiprakis. Surgery is used to remove the cancerous tumour and is often used in combination with radio- or chemotherapy. Radiotherapy uses ionising radiation directed to kill cancer cells and is often applied to treat tumours localised to one area of the body. Ionising radiation damages DNA, resulting in cell
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