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Titlebook: Coronary Vasomotion Abnormalities; Hiroaki Shimokawa Book 2021 Springer Nature Singapore Pte Ltd. 2021 Coronary Microvascular Dysfunction.

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Epidemiology of Vasospastic Anginaeactive protein, and remnant lipoprotein are significant risk factors for coronary spasm. Recently, the Japanese Coronary Spasm Association (JCSA) demonstrated that, in the temporary VSA patients, overall 5-year survival rate free from all-cause death or major adverse cardiac events was 98% and 91%,
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Pathophysiology and Molecular Mechanisms of Coronary Artery Spasmasudil, a selective Rho-kinase inhibitor, have been demonstrated for the treatment of several cardiovascular diseases in animals and humans. Thus, the Rho-kinase pathway is an important new therapeutic target in vasospasm and other cardiovascular diseases.
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Diagnosis of Coronary Artery Spasmof future cardiovascular events in patients with VSA. Ample clinical evidence has been accumulated for elucidating the detailed mechanisms of coronary artery spasm in vivo. In this chapter, we will summarize recent advances in diagnostic methodology of coronary artery spasm.
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