Titlebook: Control of the Thyroid Gland; Regulation of Its No Ragnar Ekholm,Leonard D. Kohn,Seymour H. Wollman Book 1989 The Editor(s) (if applicable)

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The Pituitary-Thyroid Regulatory Systemsystems recognized and one which has proven to be so useful clinically, it has been widely studied. The critical elements in the system are shown in the diagram in Figure 1. The best recognized level of feedback regulation is that of thyroid hormone on pituitary thyrotropin (TSH) production. However

半导体

Thyroid-Stimulating Hormone: Structure and Function, . and .. TSH is chemically related to the pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as to placental chorionic gonadotropin (CG). TSH is synthesized by thyrotropes of the anterior pituitary and stored in secretory granules. TSH is released int

FRONT

世俗

Regulatory Peptides in the Thyroid Gland origin and develop from the thyroglossus duct in the floor of the pharyngeal cavity(1,2). The C cells are thought to derive from the neuroectoderm(3). The C cell precursors migrate to form the ultimobranchial bodies which persist as separate organs throughout life, in submammalian vertebrates(4,5).

世俗

Receptors of the Thyroid: The Thyrotropin Receptor is Only the First Violinist of a Symphony Orchestlycoprotein hormone, thyrotropin (TSH). Studies of the mechanism by which thyrotropin regulates thyroid cells have been a dominant part of thyroid research for the past several decades because autoantibodies to the TSH receptor have been implicated in the hyperfunction and goiter of autoimmune Grave

aggrieve

侵略主义

G Protein-Linked Receptors in the Thyroidduce a cellular response. In thyroid cells, as in many other cells, growth and differentiation as well as specialized functions such as iodide fluxes and thyroglobulin synthesis are regulated in the above general manner. This chapter is intended to provide an analysis of the types of receptors which

记忆

ADP Ribosylation and G Protein Regulation in the Thyroid mediate the effect of other agonists such as acetylcholine (2) and phorbol esters (3). Furthermore effects of TSH on desensitization (4) and .P incorportation into phospholipids (1) are not mediated by cAMP. The phosphatidylinositol 4,5-bisphosphate cascade which increases intracellular Ca. and act