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Titlebook: Control of Gene Expression by Catecholamines and the Renin-Angiotensin System; Heinz Rupp,Bernard Maisch Book 2000 Springer Science+Busine

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https://doi.org/10.1007/978-3-658-43404-5 of mechanical steps coupled with the use of a magnet to retain iron-laden vessels. Membranes were prepared and the expressions of G. G. G. and G. were evaluated by Western immunoblotting. Baseline MAP (124 ± 6 mmHg) was only marginally (p > 0.05) higher in SHR when compared with WKY rats (110 ± 4 m
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Regulation of tumor growth and metastasis of human melanoma by the CREB transcription factor familyREB-transfected MeWo cells were reduced due to the downregulation of the CRE-dependent expression of the type IV collagenase MMP-2 and the adhesion molecule MCAM/MUC18. In the second mechanism, CREB and its associated proteins act as survival factors for human melanoma cells. Here we demonstrated th
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Attenuation of macrophage apoptosis by the cAMP-signaling systemate Ac-DEVD-AMC), and mitochondrial membrane depolarisation (Δψ). Western blots detected accumulation of the tumor suppressor protein p53, relocation of cytochrome c to the cytosol, and expression of the antiapoptotic protein Bcl-x.. Prestimulation with lipophilic cAMP-analogs attenuated apoptosis w
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Catecholamines induce IL-10 release in patients suffering from acute myocardial infarction by transaay in monocytic cells. A cAMP responsive element (CRE) was identified as major target. Here we show that there is no influence of catecholamines on the IL-10 promoter activity in T-cells. In contrast to monocytic cells, in T-cells cAMP-induced PKA-dependent phosphorylation of the CRE-binding protein
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Regulation of tyrosine hydroxylase gene transcription by the cAMP-signaling pathway: Involvement of in forming specific DNA/protein complexes with the CRE of the TH gene. To address the transcriptional activation function of individual factors, we replaced the TH CRE with a GAL4-binding site and cotransfected this modified TH promoter-reporter gene with an effector plasmid that encodes GAL4-fused
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Functional cross-talk between the cyclic AMP and Jak/STAT signaling pathways in vascular smooth musced migration (chemotaxis) of vascular SMC [10, 11], although its effect is less prominent than that of platelet-derived growth factor (PDGF). The cellular mechanisms underlying these diverse actions of Ang II are not clearly understood but are likely to involve the activation of distinct signaling p
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