Titlebook: Contributions of Physiology to the Understanding of Diabetes; Ten Essays in Memory Gaston R. Zahnd,Claes B. Wollheim Book 1997 Springer-Ver

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Anabolic Response to Cell Swelling in the Liver,lic response of the cell. This proposal was confirmed by the observation of its effect on protein synthesis/breakdown. This chapter briefly describes our wanderings through this field and summarizes our findings and the observations made by others. It also deals with the more recent concern with the anabolic signalling triggered by cell swelling.

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Insulin-like Growth Factor: Endocrine and Autocrine/Paracrine Implications and Relations to Diabeteother, was found to be on the order of 45%. The IGFs consist of an A-and a B-chain, a conserved connecting peptide which is shorter than the C-peptide of insulin and a D-domain. Many years before the chemical characterization of IGFs, biological features of impure preparations of IGFs were clearly shown to have insulin-like properties.

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-specialities. Fundamental studies on the heterogeneous diabetic syndrome are oriented towards regulatory principles of cell metabolism, genetic control mechanisms of insulin biosynthesis and secretion, as well as autoimmune events implicated in selective destruction of pancreatic ß-cell. In paralle

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Springer Series in Information Sciencesg stimulated by this phenomenon to the point that I began to think about my own “six degrees of separation” with others. One individual stood out in this paradigm—Albert E. Renold. In many ways I and many other scientists who knew him were influenced by the extraordinary character of this exuberant, cultured, and humane man.

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