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Titlebook: Contemporary Topics in Molecular Immunology; R. R. Porter,G. L. Ada Book 1977 Springer Science+Business Media New York 1977 antibody.immun

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urred area between the two, when the chemist is aware of the full significance of the biological problems, and the biologist is alert to the contribution that a knowl­ edge of molecular structure can be made to their solution. The range of scientific disciplines able to contribute to research in imm
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Creating Data and Presentation Extensions,ain basic structure, and in addition, the structural nature of antibody diversity started to unfold with the early comparative amino acid sequence studies of myeloma protein chains. It became clear, therefore, that diversity of antibodies was of genetic origin, and a new wave of theoretical speculation could be put to the test.
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Quantitation of Antibody Genes by Molecular Hybridization,ain basic structure, and in addition, the structural nature of antibody diversity started to unfold with the early comparative amino acid sequence studies of myeloma protein chains. It became clear, therefore, that diversity of antibodies was of genetic origin, and a new wave of theoretical speculation could be put to the test.
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Structural Studies in Solution on the Combining Site of the Myeloma Protein MOPC 315,posed on the basis of chemical data. These ideas included the basic two-chain immunoglobulin structure, the location of the antigen-binding site, and the concept of domain structure. These features are summarized in Fig. 1, for an IgG molecule.
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