Titlebook: Contemporary Topics in Immunobiology; Volume 3 M. G. Hanna,Max D. Cooper,Noel L. Warner Book 1974 Plenum Press, New York 1974 antigen.immun

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On the Relationship Between Cellular and Humoral Antibodies,st foreign material, antigen. At least two major groups of lymphocytes can be recognized, namely, s.c. B and T lymphocytes (.., 1969; Cooper .., 1966). B cells derive their name from their site of immunological maturation in birds, namely the bursa of Fabricius (Cooper .., 1966), but the correspondi

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T Cell Modification of B Cell Responses to Antigen in Mice,oitt ., 1969). The circulating pool of lymphocytes (Gowans and McGregor, 1965) is a mixture of T and B cells in mice (Sprent and Miller, 1972) and rats (Howard ., 1972; Strober, 1972), and, as a consequence, all peripheral lymphoid organs (e.g., spleen and lymph nodes), lymphatic channels such as th

污点

Genetic Control of Antibody Responses to Myeloma Proteins of Mice,vy chain constant regions (C. genes). The existence of allotypic forms of mouse immunoglobulin has permitted the establishment of the genetic relationship between the C. genes for different classes of immunoglobulins (Potter and Lieberman, 1967. and also the determination of the linkage between C. g

过度

过度

Antigen-Binding Receptors on Lymphocytes,s been central to immunologic theory since it was originally proposed by Paul Ehrlich (1900). Direct evidence for the existence of such receptors has been amassed in recent years. In particular, it has been demonstrated that in nonimmunized animals, rare lymphocytes will bind a given substance to th

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Modification of B Lymphocyte Differentiation by Anti-Immunoglobulins,hose involved in antibody production has greatly stimulated research on the cellular aspects of immunity. Recognition that B and T cells are separate populations has led to the definition of morphologic and functional markers for these cell lines. These markers have made it feasible to study the ear

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The Roles of T and B Lymphocytes in Self-Tolerance and Autoimmunity,body fluids from other animals they do not as a rule make antibodies against their own tissue constituents. He termed the phenomenon “horror autotoxus,” but was unable to advance any satisfactory explanation for it. While developing the clonal selection theory of immunity, Burnet (1959) postulated t

转向

Language Integrated Query (LINQ),lden age of ‘thymology’” (Miller, 1967). A second golden age (Miller, 1967) began with the discovery that thymus-derived lymphocytes [soon to be christened T cells (Roitt ., 1969)] did not themselves make circulating antibodies, but rather assisted other nonthymus-derived lymphocytes to do so (Mille