Titlebook: Contemporary Topics in Immunobiology; Self/Non-self Discri John J. Marchalonis,Nicholas Cohen Book 1980 Springer Science+Business Media New

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Salamanders and the Evolution of the Major Histocompatibility Complex,s intimately involved with the immune responses of that species (Götze, 1977). This gene cluster is called the major histocompatibility complex, or MHC. Products of genes within this complex induce differentiation of T cells, as measured by blast-cell transformation, clonal expansion, and the develo

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Idiotypes, T-Cell Receptors, and T-B Cooperation,interactions among a variety of different cell types. The hallmarks of the mammalian immune system — specificity, inducibility, memory, and regulation — have been conclusively shown to be associated with lymphocytes (Gowans, 1970). The division of lymphocytes into two major classes, known as T cells

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The Biological Function of the Major Histocompatibility Complex: Hypotheses,mous scientific interest during the past thirty to forty years. The MHC, which is known under a variety of names, depending on the species (Table I), has been shown to play a key role in a variety of immunological and physiological phenomena (Table II). It has become increasingly apparent that under