Titlebook: Conducting Clinical Trials; Frank L. Iber,W. Anthony Riley,Patricia J. Murray Book 1987 Plenum Publishing Corporation 1987 clinical resear

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https://doi.org/10.1007/978-3-662-70140-9, and leisurely inquiry about symptoms, variations from the baseline or normal ranges are encountered 5 to 15% of the time. Should an intercurrent viral infection arise, extreme muscular exertion occur, or severe anxiety develop, biochemical and symptomatic abnormalities will concomitantly increase.

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Budget Planning and DevelopmentA budget is awarded as a part of each contract to conduct drug or device research and to a large degree determines what can be accomplished as a part of the investigation. A budget can be developed only through careful planning of exactly how the study will be carried out.

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Vladimir A. Shekhovtsov,Johann Ederthe research protocol and its proper execution. The protocol physicians derive benefit from the completion of the protocol and, therefore, are considered to some degree in a conflict of interest with pure advocacy of what is beneficial for the patient (see Spiro, 1986).

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Book 1987jor expansion into the clinical trials market. The company‘s unique concept of clinical research held great promise and had suc­ cessfully endured many of the fits and starts characteristic of entrepre­ neurial organizations. With a staff of highly enthusiastic, albeit inex­ perienced, field personn