Titlebook: Concomitant Continuous Infusion Chemotherapy and Radiation; Marvin Rotman (Professor and Chairman, Dept. of Ra Textbook 1991 Springer-Verl

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Strategies for Overcoming Challenges,ally hypoxic cells thought to exist in many human tumors. A recent study examining the patterns of failure following radiation treatment for high grade brain tumors revealed that 78% of unifocal tumors recurred within 2 cm of the enhancing edge of the tumor, as demonstrated by the CT scan (W. et al.

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Textbook 1991fects resulting from the administration of commonly used drugs, such as 5-fluorouracil, cisplatinum and adriamycin, with concomitant radiation therapy. Much of the data has never before been published. The wealth of information in this volume makes it a valuable reference; at the same time it gives

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Experimental Rationale for Continuous Infusion Chemotherapydemonstrated the importance of dose intensity for optimal antineoplastic effect. The administration schedule required to achieve maximal dose intensity, however, is not the same for every drug. The pharmacodynamic response to any drug is a function of concentration and duration of exposure. The simp

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Combination Chemotherapy by Infusion in Hematological Malignanciesnt of hematological malignancies. For the past decade our group has been interested in the use of infusional chemotherapy in the treatment of lymphomas. The following discussion will review our experiences and those of others in this area. We will also comment on work by other investigators on the u

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