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Titlebook: Concomitant Continuous Infusion Chemotherapy and Radiation; Marvin Rotman (Professor and Chairman, Dept. of Ra Textbook 1991 Springer-Verl

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书目名称Concomitant Continuous Infusion Chemotherapy and Radiation
编辑Marvin Rotman (Professor and Chairman, Dept. of Ra
视频video
丛书名称Medical Radiology
图书封面Titlebook: Concomitant Continuous Infusion Chemotherapy and Radiation;  Marvin Rotman (Professor and Chairman, Dept. of Ra Textbook 1991 Springer-Verl
描述The administration of chemotherapeutic agents by continuous infusion with concomitant radiation therapy heralds a new approach in the treatment of cancer. This comprehensive book on the subject includes, besides a discussion of its scientific basis, the most promising clinical data on the use of continuous infusion chemotherapy and radiation. Thus, it is an important update for clinical investigators involved in frontline research as well as for practicing physicians participating in the direct care of cancer patients. The contributions include the latest results of this new approach in a number of tumor sites. There is a detailed description of the principles of radiosensitization for malignant tumors and radioprotection for normal tissues; these are the principles which have led to concrete clinical applications. There is also a presentation of the most recent data on the beneficial effects resulting from the administration of commonly used drugs, such as 5-fluorouracil, cisplatinum and adriamycin, with concomitant radiation therapy. Much of the data has never before been published. The wealth of information in this volume makes it a valuable reference; at the same time it gives
出版日期Textbook 1991
关键词Tumor; brain; brain tumors; cancer; cancer treatment; carcinoma; cell; chemotherapy; clinical trial; metastas
版次1
doihttps://doi.org/10.1007/978-3-642-84186-6
isbn_softcover978-3-642-84188-0
isbn_ebook978-3-642-84186-6Series ISSN 0942-5373 Series E-ISSN 2197-4187
issn_series 0942-5373
copyrightSpringer-Verlag Berlin Heidelberg 1991
The information of publication is updating

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Time-Specified Delivery of Chemotherapy by Implantable Programmable Pumps — Preliminary Data on 5-Fltotoxic therapy. The treatment goal for these metastatic tumors is palliation, not cure. As chemotherapy may not even prolong survival significantly, its application needs to be critically reviewed as to how it affects the patient’s quality of life.
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Glutathione, a Determinant of Response to Cancer Treatmentth the responsive tumor types and the much broader spectrum of malignancies in which chemotherapy usually plays at best a palliative role have allowed the establishment of a number of principles that may allow the rational design of curative treatment for most cancer.
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https://doi.org/10.1007/3-7908-1705-8and poor quality of delivery, coupled with disappointing results and significant morbidity, caused surgeons to remain antagonistic. Once supervoltage irradiation became available, results improved and it was possible to treat patients to tumoricidal doses within normal tissue tolerance dose levels.
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https://doi.org/10.1007/978-981-13-7685-6r, demonstrate a marked schedule dependency - i.e., at equivalent AUCs, a prolonged infusion will yield much greater tumor cell kill than a shorter infusion or bolus. Other anticancer drugs may exhibit a marked concentration dependency, such that the reverse is true.
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