| 书目名称 | Concepts in Biochemical Pharmacology |
| 副标题 | Part 3 |
| 编辑 | James R. Gillette,Jerry R. Mitchell |
| 视频video | |
| 丛书名称 | Handbook of Experimental Pharmacology |
| 图书封面 |  |
| 描述 | Part 3 of the Handbook of Experimental Pharmacology (Concepts in Biochem ical Pharmacology) applies the principles enunciated in Parts 1 and 2 to clinical pharmacology and toxicology. The major objective is to elucidate the many factors that determine the relationships between pharmacokinetic aspects of the disposition and metabolism of drugs and their therapeutic or toxic actions in man. Because of the more restricted information obtainable in human studies, this volume reflects the editors‘ bias that an understanding of pharmacokinetics is fundamental for assessing pharmacologic or toxicologic effects of drugs in humans. The first chapter is a unique primer on when to apply and how to use pharmaco kinetic tools in human pharmacology. The second chapter explains the general assumptions underlying pharmacokinetic approaches both in simple terms for the novice and in mathematical form for the more sophisticated reader. Several chapters on determinants of drug concentration and activity discuss drug absorption, drug latentiation, drugs acting through metabolites, entero hepatic drug circulation, influence of route of drug administration on response, genetic variations in drug disp |
| 出版日期 | Book 1975 |
| 关键词 | absorption; drug; kinetics; metabolism; pharmacokinetics; pharmacology; research; toxicology |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-46314-3 |
| isbn_softcover | 978-3-642-46316-7 |
| isbn_ebook | 978-3-642-46314-3Series ISSN 0171-2004 Series E-ISSN 1865-0325 |
| issn_series | 0171-2004 |
| copyright | Springer-Verlag Berlin · Heidelberg 1975 |
发表于 2025-3-21 16:46:27
