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Titlebook: Computer Analysis of Sequence Data, Part I; Annette M. Griffin,Hugh G. Griffin Book 1994 Humana Press 1994 Alignment.DNA.DNA sequencing.En

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书目名称Computer Analysis of Sequence Data, Part I
编辑Annette M. Griffin,Hugh G. Griffin
视频videohttp://file.papertrans.cn/234/233456/233456.mp4
丛书名称Methods in Molecular Biology
图书封面Titlebook: Computer Analysis of Sequence Data, Part I;  Annette M. Griffin,Hugh G. Griffin Book 1994 Humana Press 1994 Alignment.DNA.DNA sequencing.En
描述DNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gen- ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods ess- tial to analysis, and a familiarity with computers and sequence ana- sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Analysis of Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or p- tein) sequences. Each chapter is written such that a competent sci- tist with basic computer literacy can carry out the procedure successfully at the first attempt by si
出版日期Book 1994
关键词Alignment; DNA; DNA sequencing; Endoplasmatisches Reticulum; Internet; RNA; Secondary structure; calculus; c
版次1
doihttps://doi.org/10.1385/0896032469
isbn_softcover978-0-89603-246-0
isbn_ebook978-1-59259-511-2Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 1994
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GCG: Displaying Restriction Sites and Possible Translations in a DNA Sequence,“enzymes”). Positive hits are displayed as a function of the sequence coordinate plotted vs the patterns found. In order to view the result with respect to the amino acid sequence (provided that the DNA sequence does have a reading frame), automatic translation can be achieved by using either a stan
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GCG: Database Searching,e-comparison. It would take much too long to calculate alignment path matrices between the database sequence and the query sequence. However, calculation precision is still needed, because searching a “small” database of 10,000 sequences can no longer be controlled interactively by the researcher. T
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