Titlebook: Computational Methods in Systems Biology; First International Corrado Priami Conference proceedings 2003 Springer-Verlag Berlin Heidelberg

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Demographic and Family Trends in Asiallows the simulation the sensi- tivity of the ERK pathway to variations of initial RKIP and ERK-PP (phosphorylated ERK) concentrations along with time. Throughout the simulation study, we can qualitatively validate the proposed mathemati- cal model compared with experimental results.

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https://doi.org/10.1007/978-3-662-66791-0checker NuSMV and the constraint-based model checker DMC, for the modeling and querying of two biological processes: a qualitative model of the mammalian cell cycle control after Kohn‘s diagrams, and a quantitative model of gene expression regulation.

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Limpid

Formal Modeling of C. elegans Development: A Scenario-Based Approachof the methods and logic of data collection and analysis in the field of developmental genetics with the languages, methods and tools of scenario-based reactive system design. In particular, we use the recently developed methodology consisting of the language of . with the . process, to model the we

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Graphs for Core Molecular Biologyexpressed as graph rewriting rules. A compilation in a low-level graph rewriting calculus, called .., is given and shown to be correct up to some suitable notion of observational equivalence. This intermediate language is of independent interest and can be easily implemented in π-like calculi.

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Contribution of Computational Tree Logic to Biological Regulatory Networks: Example from Pseudomonass evolved by René Thomas which constitute the semantic of our formal approach. We illustrate this formal language with the system of mucus production in ., which is a mucoid bacteria that plays an important role in the cystic fibrosis. With the Thomas’ theory, we could wonder if the mucoid state cou

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