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Titlebook: Computational Methods in Systems Biology; 10th International C David Gilbert,Monika Heiner Conference proceedings 2012 Springer-Verlag Berl

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Multi-objective Optimisation, Sensitivity and Robustness Analysis in FBA Modellingensitivity Analysis of the metabolic model, which finds the inputs with the highest influence on the outputs of the model. We show that our methodology provides effective vision of the achievable synthetic strain landscape and a powerful design pipeline.
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Population Dynamics P Systems on CUDA to achieve up to a 7x speedup on a NVIDA Tesla C1060 compared to an optimized multicore version on a Intel 4-core i5 Xeon for large systems. Other results and testing methodologies are also included.
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https://doi.org/10.1007/978-3-031-06641-2eover, an analytic expression of the growth rate during the exponential phase as function of the input is derived. A relevant problem is that of identifiability of the parameters of this expression supposing noisy measurements of exponential growth rate. We present such an identifiability study that we validate . with synthetic measurements.
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Accounting for Mental Reference,ed environment; (.) we introduce classification of acceptable parametrizations to identify most optimal ones; (.) we propose two ways of visualising parametrizations dynamics wrt time-series data. Finally, computational efficiency is evaluated and the methodology is validated on bacteriophage . case study.
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How Regulations Impact Investment Managerstranslation at the nucleotide and codon levels, we investigate the effects of the codon sequence on the dynamics of single gene expression and of a genetic switch. We find that the ribosome binding site region sequence affects mean expression rates. In the genetic toggle switch, the sequence is shown to affect the switching frequency.
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