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Titlebook: Complex Systems in Medicine; A Hedgehog’s Tale of David C. Aron Book 2020 Springer Nature Switzerland AG 2020 Clinical Diagnosis.Complex Pa

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Managing Patients: Evidence-Based Medicine Meets Human Complexityences can result from intra-individual and extra-individual factors. Intra-individual factors can occur at any level of the hierarchy of biological organization, each of which consists of an extensive network of interacting elements. This issue is presented as one of the nature of the intervention b
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Taking Complex Systems into Account When Teaching About Diabetesis was illustrated with a case of a patient with diabetes. In addition to addressing issues at various levels, this framework also provided opportunities to think about other aspects of complex systems. Each level could be conceptualized as a network with interactions among the components that were
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Using Analogies to Make Connections Between Seemingly Disparate Systems: The Case of Patient Safety only understood, but also to which they granted legitimacy. It had to be molecular biology. After eliciting some of the design principles one might use to ensure patient safety, e.g., robustness, resilience, redundancy, shared functions, and adaptability, the specifics of the DNA damage response an
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The Complexity of Contextresented relevant to implementation of an intervention in an organization. First, implementation is a function of the interaction between intervention and context. Second, sustainability is equal to the degree to which the intervention becomes part of the context, i.e., − just the way we do business
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Precision Medicine and Complexityed in vivo, i.e., a new context. What is missing is the intervention x context interaction where the abnormal (or synthetic) gene is the “intervention.” Conceptualizing cancer as a dynamic complex system that emerges from the microenvironment in which it is embedded can help explain these observatio
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